A : An IUI — intrauterine insemination is a process when washed sperm is injected into the uterus through a thin flexible catheter threaded through the cervix. The Whole process takes only a few minutes — involving the insertion of a speculum and then the catheter with sperm. A : Ideally an IUI should be performed within 6 hours either side of ovulation.
Some doctors believed that in male factor infertility, insemination should be performed after ovulation. With other causes, the chances of success are higher with insemination before ovulation with the sperm waiting for the egg.
Some doctors base timing of IUI on a natural LH surge where a single IUI at 36 hours is the norm, but doing them at 24 hours is also pretty common since ovulation may be a bit earlier. When two inseminations are planned, they are usually timed between 24 and 48 hours after the surge is detected. Sometimes, ovulation is induced by giving hCG injection, especially in cases when fertility drugs are used.
Typical timing would be to have a single IUI at about 36 hours post-hCG, though some do it at 24 hours. If two IUIs are scheduled, they are usually spaced at least 12 hours apart between 24 and 48 hours after the hCG. A : Clomiphene citrate is the common oral drug used to induce ovulation.
Dosage starts from 50 mg daily for 5 days from Day 6 to 9 of the menstrual cycle and if there is no ovulation, some doctors use incremental dosage up to mg to get a better response. Fertility hormones like follicular stimulating hormone FSH and human menopausal gonadotropins HMG are the common drugs used to induce ovulation.
They come in the form of injections and are commonly used by fertility specialists. Patients on injectables require more stringent monitoring to avoid ovarian hyperstimulation syndrome, a complication that may require hospitalisation.
Age of the women and sperm quality seemed to have a major influence on the success rates. Another influencing factor is the sperm count. Higher sperm count increase the odds of success, however, there was little difference between success with good-average counts and those with high counts. A : Most women consider IUI to be fairly painless, very similar to having a pap smear. Some patients experienced cramps, but often what is felt is ovulation-related rather than from the IUI.
Patients should not feel the catheter since the cervix is slightly opened during ovulation. A poorly timed IUI might cause more discomfort at the cervix. A : Washed sperm normally live for hours, but, sometimes as long as 24 to 48 hours. It should not be kept for too long. Thus, the timing for IUI is so important that it is advisable to do insemination within 3 hours. An abstinence time of less than the recommended time may result in a lower count as well as his body is not able to replenish the mature sperm in time.
This comes in handy if you will be unable to collect a specimen on the day of the IUI for any reason such as travelling or difficulty in collecting. We hope these tips will help to de-stress specimen collection on the day of your next IUI! Contact us for more information. Click here to cancel reply. Name required. Washing is the first step of preparation of sperm sample for IUI. It involves separation of the sperm cells from the seminal fluid.
This process, in addition to removing toxins, also increases the chances of the sperm reaching the fallopian tubes by increasing its fertilizing capacity. Hence it can also aid couples with unexplained infertility or immune system disorders. The separation of sperm cells from the seminal fluid and any cryoprotectant is commonly done using three techniques.
Collection of The Sperm Sample Collection of the sperm sample should be done after two to five days of sexual abstinence and not less or more. What is Sperm Washing? Techniques Used for Sperm Washing The separation of sperm cells from the seminal fluid and any cryoprotectant is commonly done using three techniques.
Basic sperm wash: In this process, a solution containing protein supplements and antibiotics are added to the sample and centrifuged repeatedly. Within a time duration of 40 minutes, the seminal fluid separates itself from the cells thereby concentrating the cells alone.
Density gradient sperm wash : One of the popularly used techniques, this method separates the dead sperm cells, white blood cells and other elements in addition to the seminal fluid. The semen is placed on the top layer of a test tube filled with liquids of varying densities. During centrifugation, the healthy sperm cells move to the bottom layer of the tube while the remaining particles stay on top.
Swim up technique: This technique relies on the motility and strength of healthy sperm cells. The semen is placed in a test tube with a layer of culture medium, where only the healthy cells move towards the culture where they are collected in order to be used for IUI. How long does it take for the embryo to implant in the uterus? Know More. How much does it cost to get your eggs frozen? How much does it cost to adopt an embryo? What Common conditions that affect male infertility is teratospermia?
What happens during and after implantation?
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